Planarians on nicotine

Some of the work that I do on my own research is about the behavioral pharmacology of abused drugs.  I have talked about it here and here.  Nicotine is without a doubt one of the most abused drugs ever, and it does indeed affect planarians.

Here is a short video showing the response of a planarian to nicotine compared to another planarian placidly gliding underwater.

Here’s a question for my loyal followers, would you like to know more about planarian research and on planarian pharmacology in particular?

If you want to know more

Rawls SM et al. (2011) Nicotine Behavioral Pharmacology: clues from planarians.  Drug Alcohol Depend. 2011 Nov 1;118(2-3):274-9.

Pagán OR et al. (2009) A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms.  Eur J Pharmacol. 2009 Aug 1;615(1-3):118-24

planarianswellsmall

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
If you want to know more of my scientific research you can click here.

Want to see what my blog is about? Go here for some other posts. You can also subscribe to my blog! Just go to the “Home” page, right hand side.

Comment here or send me a message if you have any questions! My email is: orpagan@yahoo.com.

I wrote a popular science book! >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>tfb-cover1

For more details about my book, click here for my Amazon.com author page.

For my Facebook page click here.

My Twitter name is @Baldscientist

For the customary disclaimers go to my “About” page.

Advertisements

5 thoughts on “Planarians on nicotine

  1. Pingback: Do planarians need their brain to react to abused drugs? Well, it depends on the drug… | Baldscientist

  2. Heh, why not make eeetsy beestsy cigarettes and see if “oral fixation” enhances the rate of addiction…planarians do have mouths, after all….

  3. Do planarians provide any insights into curing addiction? ie, is cold turkey more effective than gradual weaning? I know people that struggle to quit smoking only to become addicted to nicotine gum and end up taking higher doses than they ever got when smoking, which to my mind makes a return to smoking more likely, not less.

    • That is the big question, Peter. As interesting as it is, it is very difficult to extrapolate behaviors from worms to humans. Addiction, after all has a very strong psychological component. What we are hoping right now is to try to get a better idea of the physiological mechanisms for addiction in general using the worms. Time will tell…

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s